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Table 30 Aripiprazole for children and adolescents with Anorexia Nervosa

From: Canadian practice guidelines for the treatment of children and adolescents with eating disorders

Certainty assessment

Impact

Certainty

Importance

№ of studies

Study design

Risk of bias

Inconsistency

Indirectness

Imprecision

Other considerations

Weight

 1

Case Control

serious a

not serious

not serious

not serious

none

Retrospective case-control study with 22 subjects treated with aripiprazole, 84 no treatment. BMI was slightly different between groups 18.8 vs. 17.9 p < 0.35.

VERY LOW

CRITICAL

Weight

 2

Case Reports

very serious a,b

not serious

not serious

not serious

none

5 cases report a benefit in terms of weight gain

VERY LOW

CRITICAL

  1. Explanations
  2. athe study was not randomized
  3. bthere are five cases reported on in total with no comparison group
  4. Bibliography:
  5. Case Control - Frank 2017 [165]
  6. Case Reports - Frank 2016 [166], Trunko 2011 [167]